Suggestions(3)
Exact(2)
In general, he sees markets not as mediating a balance between supply and demand but as favoring one constituency over another.
From these findings we conclude that the transcriptional MBD2 repressor and ERα transactivator co-participate to the regulation of pS2 expression by mediating a balance between repressive histone H3 lysine 9 trimethylation and active histone H3 acetylation marks at pS2 promoter.
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Since the only difference between these two cell lines are COX-2 and that could mediate a balance between apoptosis and cell survival, we analysed the expression of COX-2 along with its transcription factor NFκB. Decreased expression of cox-2 transcripts in 75 µM plumbagin treated HT29 indicates that COX-2 plays a crucial role in plumbagin induced apoptosis.
Therefore, the edited let-7a-5C may play a role for mediating a proper balance between MMP-2 level and embryo invasion for the successful pregnancy through Smad7.
Thus, Baicalin appeared to play a dual role in T-cell differentiation by mediating a reciprocal balance of Foxp3 and RORγt.
The critical gene, well known for its role in suppressing tumors, seems to mediate a profound balance between life and death.
Thus, SIRT1 appears to mediate a delicate balance between its anti-growth and pro-growth properties.
Of note, the increased release of insulin after loss of Ago2 expression in the β cells of ob/ob mice improved many aspects of the diabetic phenotype, including circulating glucose and insulin levels, and glucose tolerance; however, this came at the expense of β cell mass and may suggest that the miRNA pathway mediates a delicate balance between both growth and secretion.
Probiotics can reverse immunological disturbances by inducing immunoregulatory responses mediating a control of the balance between pro- and anti-inflammatory cytokines [25], [26].
Histone acetylation is mediated by a balance between histone acetyltransferases (HATs) and the three classes of histone deacetylases (HDACs): Class 1 (HDAclass8), class 2 (HDand-7,9-11), and class 3 (Sirt1-7).
DOI: http://dx.doi.org/10.7554/eLife.06462.019 We further propose that chromosome movement on acentrosomal spindles is mediated through a balance of plus- and minus-end directed forces operating on chromosomes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com