Sentence examples for mediating Runx2 responses from inspiring English sources

TIEG1 is also shown to play an important role in mediating Runx2 responses to cytokines in osteoblast cells.

This study demonstrates that TIEG1 not only directly regulates Runx2 expression in osteoblasts, but also plays an active role in mediating Runx2 responses following TGFβ1 and BMP2 treatment.

As a result, we were interested in determining whether integrin α3β1 may play a role similar to αvβ3 in mediating TLR2 responses to the organism and to purified TLR2 ligands.

Interestingly, we found that the kinase function of SYK was important for mediating TLR9 responses.

Notably, the stomachs of animals colonized with the morphologically locked mutants had reduced levels of IL-1β, IL-6 and IL-17; all of which are involved in mediating Th17 responses (Hernandez-Santos and Gaffen, 2012).

For each consecutive stimulus, the travel distance of probe was increased by 1 μm (B ) Yoda1 (25 μM) mediates Ca2+ responses (384-well FLIPR) in HEK cells transiently transfected with mPiezo1.

These findings are consistent with those previously obtained for H1 histamine receptor-mediated Ca2+ responses, where desensitization is masked by the presence of significant cell/tissue receptor reserve with respect to the observed response.

To clarify and extend understanding of the roles of Rho proteins in FcεRI signaling, we first investigated whether the C-terminal di-arginine motif is needed for Cdc42 to mediate Ca2+ responses and exocytosis in mast cells.

Mig and IP-10, both ligands for the CXC receptor (CXCR 3, are attractants for lymphocytes mediating Th1-type responses in the RA enflamed joint.

It is interesting to note that a major role for Syk in mediating NLRP3-dependent responses has not been reported for bacterial infections.

These data give new insight into the role of IL-23 in mediating Th17 IL-22 responses, but not IL-17 responses.