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The abscission machinery, including the ESCRT complex, is assembled at the midbody in a highly regulated stepwise process (Agromayor and Martin-Serrano, 2013; Guizetti and Gerlich, 2010; Schiel and Prekeris, 2013), and mediates the separation of daughter cells by fission of the midbody.
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Reviewer #1 The authors of this paper are attempting to advance the hypothesis that mechanical stress in the shoot apical meristem turns on expression of the STM transcription factor which then acts to mediate the separation between organs.
For elucidating the sophisticated mechanism that mediates the perilous separation of duplicated chromosomes during cell division and thereby prevents genetic diseases such as cancer.
The endosomal sorting complexes required for transport (ESCRT) machinery mediates the physical separation between daughter cells during cytokinetic abscission.
The Diabetes Control and Complications Trial (DCCT) has documented the profound beneficial effects of intensive diabetes therapy (INT) compared with conventional therapy (CON) on the development and progression of microvascular and neuropathic complications during the DCCT, mediated by the separation of HbA1c levels between the two treatment groups (1).
The 2A moiety mediates cotranslational separation of the growing polypeptide chain [25].
The significantly improved photocatalytic activity can be mainly ascribed to the formed CNT-mediated Z-scheme heterojunction, which facilitates the separation and transfer of photogenerated electron-hole pairs.
Data suggest that this adhesion is mediated by homophilic interaction of Chp, while the separation requires the cooperative function of Prom and Eys.
It mediates centrosome separation and formation of the bipolar mitotic spindle, which is important for cell mitosis.
The mitotic spindle is a MT super-structure which mediates chromosome separation during cell division.
The separation unhinged her.
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