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Guanine nucleotide binding protein (GNAO1) mediates the physiological effects of various neuronal receptors [ 35].
It was also hypothesized that ghrelin mediates the physiological responses of tissues which surround the tumor, to malignant changes [ 34].
The cholecystokinin-B (CCK-2) receptor mediates the physiological effects of gastrin, including growth promoting effects on pre-malignant and malignant colonic mucosa (Smith and Watson, 2000).
ERβ, which showed the strongest association with BPA exposure, is one of two ER subtypes that, along with ERα, mediates the physiological actions of estrogens (Swedenborg et al. 2009).
As an active constituent of G-protein, G-α-o is widely believed to couple with, and mediates the physiological effects of, a variety of neuronal receptors, such as GABA (γ-aminobutyric acid) receptor B, dopamine D2 receptors and somatostatin receptors [ 8].
This is the normal physiological compound in the body of humans that mediates the physiological inhibition of the function of the central nervous system.
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To our knowledge, this represents the first observation of miRNA mediating the physiological action of a hormone in the development of the liver.
These unexpected targets could, in some cases, mediate the physiological effect of a drug, even if the drug is designed specifically to target one particular protein [2].
Corticotropin-releasing factor (CRF) is involved in mediating the physiological and behavioral responses to stress [ 1- 5].
Indeed, it was recently suggested that FGF21 may play a role in mediating the physiological consequences of TZD treatment [ 7].
In addition to A β, the ectodomain of APP has been reported to have neuroprotective effects and mediate the physiological functions of APP.
More suggestions(15)
mediates the first
mediates the cellular
mediates the key
mediates the CES-later
mediates the multiple
mediates the IFN-γ
mediates the cytotoxic
mediates the proteasomal
mediates the physiologic
mediates the nuclear
mediates the insulin-signaling
mediates the intestinal
mediates the spontaneous
mediates the dorsalizing
mediates the indirect
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