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It mediates the movement of DNA within and between genomes.
It has been shown that MCP-1, secreted by the adipose tissue macrophages, mediates the movement of the circulating monocytes to the adipose tissue to further enhance the inflammatory potential of the adipose tissue (10, 11).
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Although many flux studies have been conducted in the past, the recent discoveries of the scavenger receptor B1 (SR-B1) and ATP binding cassette 1 (ABCA1), which mediate the movement of cholesterol between cells and extracellular acceptors, has led to increased interest in studies of cellular cholesterol flux.
The importin α (also called karyopherin α) family comprises soluble transport factors that mediate the movement of proteins from cytoplasm to the nucleus in interphase cells [1].
Cellular eEF-2 plays an essential role in translation by mediating the movement of the transfer-RNA bound nascent polypeptide chain between sites on the ribosome after addition of each amino acid [4].
Recently, MG53 was shown to interact with dysferlin and caveolin-3 to facilitate vesicle trafficking to the site of membrane injury and to mediate the movement of dysferlin to the site of injury [12].
Localization of BSCTV C4 protein and its DNA binding activity suggest that BSCTV C4 function as a nuclear shuttle protein to bind viral DNA and mediate the movement of virus between nucleus and cytosol.
Our data support a direct role of SLC4A11 in mediating the movement of water across membranes.
Thus, AEC II can mediate the movement of Cl- in both directions.
9 Specialized transport proteins, in the form of channels, carriers, and pumps, mediate the movement of heavy metals through membranes.
We hypothesize that the role of group IV-A CNGCs is to mediate the movement of cations between the central vacuole and the cytosol in response to certain types of abiotic and biotic stress.
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