Sentence examples for mediates the modulation from inspiring English sources

For GLR-1, GLR-2, and MAGI-1L to be required in the command interneurons to modulate habituation in the mechanosensory neurons, one must posit that there is either a retrograde signal that mediates the modulation or that the command interneurons regulate a separate set of neurons, which in turn act as modulators of the mechanosensory neurons.

Right: quantification of the normalized Htt signals, n = 4. DOI: http://dx.doi.org/10.7554/eLife.05449.013 The involvement of Rabgap1l gives the clue for identifying the downstream small GTPase(s) that mediates the modulation of Htt levels.

Although interactions between p53 and eIF2 α or eIF4E have been reported, the exact mechanisms through which p53 mediates the modulation of p38 on eIF2 α or eIF4E require further study.

Furthermore, the increased expression of CTLA-4 [11], [11], PD-1 [10], and Cbl-b [12] as well as modulation of the host response by secreted parasite molecules [13], [14] have also been postulated to play a role in mediating the modulation of T cell responses seen in LF.

Thus, LCDT-mediated the modulation of RACK1/BDNF in hippocampus might contribute to neuroprotective effects of LCDT.

In an effort to clarify the signaling pathway downstream of TLR4 that mediates the ACAT1 modulation and foam cell formation in VSMCs, we tested the role of MyD88/NF- κB signaling in this process.

These anorectic actions are mediated by the modulation of hypothalamic neuropeptide systems, such as melanocortins.

Thus, these results suggest that CGA is a potential therapeutic agent in the treatment of DN due to its antioxidant and anti-inflammatory effects which are mediated via the modulation of the Nrf2/HO-1 and NF-ĸB pathways.

Our data raise the possibility that the therapeutic effects of valproate in bipolar disorder may be mediated by the modulation of ER stress through the regulation of WFS1 and GRP94.

In order to discriminate between the direct effects of anti-TNF-α agents on γδ-T cells and the secondary, indirect effects that are mediated through the modulation of the inflammatory cytokine milieu in vivo, we examined the impact of anti-TNF-α agents on γδ-T cells in vitro.

This effect was mediated by the modulation of the expression and phosphorylation of cyclin-dependent kinase 2, cyclin-dependent kinase inhibitor p21, and downstream retinoblastoma protein.