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Integrin αvβ3 is a molecule which mediates the migration of endothelial cells through the basement membrane during blood vessel formation.
Recent literature indicates that CD177 mediates the migration of neutrophils across endothelial cells via interactions with proteinase 3 (Kuckleburg et al., 2012; Kuckleburg and Newman, 2013) and PECAM-1 (CD31) (Sachs et al., 2007; Bayat et al., 2010), as well as the degranulation and superoxide generation in a Mac-1-dependent manner (Jerke et al., 2011).
IP10/CXCL10 is a ligand for CXCR3, which is preferentially expressed by Th1 cells and therefore mediates the migration of Th1 cells to lesional sites.
We now provide evidence that CXCR7 is induced by hypoxia, and mediates the migration of glioma cells towards SDF-1α in hypoxic conditions.
It has been documented that Wnt5a is upregulated during pancreatic carcinogenesis and mediates the migration and invasion of pancreatic cancer cells induced by the transcription factor CUTL1 [ 15].
Additionally, MMP-11 is up-regulated by Gli1 and mediates the migration and invasion induced by Gli1 in MDA-MB-231.
Similar(47)
The present study indicates that collagen fragments can mediate the migration of bone marrow stromal cells.
In contrast, less is known about how the geometric cues mediate the migration dynamics of cells.
CCL2 signaling has been reported to mediate the migration of MDSCs [27] and arginase 1 is an important pathway for mediating the suppressor function of MDSCs [28].
We used the same chemical inhibitor approach taken with EpRas to determine what pathway was mediating the migration of PC3 cells.
Inflamed transplanted tissues can themselves produce an 'early' wave of chemokines, including Gro-β/CXCL2, Lix/CXCL5, MCP-1/CCL2, MIP-1α/CCL3 and MIP-1β/CCL4, which can mediate the migration of immune cells to the site of tissue damage or injury [9], [19].
More suggestions(15)
enables the migration
affects the migration
permits the migration
mediates the influence
mediates the transformation
mediates the reward
mediates the synthesis
mediates the uptake
mediates the pathophysiology
mediates the switch
mediates the service
mediates the regression
mediates the story
mediates the association
mediates the reduction
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