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The interaction of gp120 and co-receptor (CCR5/CXCR4) mediates the entry of HIV-1 into host cells, which has been increasingly exploited in recent years as the target for new antiviral agents.
Phagocytosis, as the main process that mediates the entry of mycobacteria into these cells, has been suggested previously [ 34, 35].
The protective antigen binds to cellular receptors and mediates the entry into the cytosol of the other two factors.
LRP-1 also mediates the entry of Aβ into vascular smooth muscle cells, where it is degraded [ 43].
The small intestine mediates the entry of nutritional lipids and is one of the main sites of β-oxidation [ 32- 34].
We found that the inhibitory effect of cefmetazole was blocked when Oatp1a4 was inhibited by intravenous administration of amiodarone, suggesting that Oatp1a4 mediates the entry of cefmetazole from the circulating blood into endothelial cells.
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Flow cytometric analysis showed that MP-g-OEI copolymers could efficiently mediate the entry of nucleic acids into cells.
EBOV preferably utilizes hTIM-1, not other TIM proteins, to mediate the entry efficiently, which suggests that hTIM-1 probably has a direct or indirect interaction with EBOV glycoprotein (GP).
Furthermore, SR-B1 was shown to mediate the entry of hepatitis C virus (HCV) in an HDL-dependent manner [21], [22], while it also plays an important role in the infection of hepatocytes by the malaria parasite [23].
Although the initial interaction of the pathogen with the host macrophage is considered a critical step in the pathogenesis of Mtb, the role of the receptors that play a role in mediating the entry of Mtb into macrophages and in transducing intracellular signals is very controversial and far from being understood.
Several endocytic mechanisms have been described to mediate the entry of material into the cells [ 24].
More suggestions(15)
mediates the switch
mediates the service
mediates the story
mediates the relationship
mediates the reduction
mediates the laser target
mediates the reward
mediates the synthesis
mediates the uptake
mediates the pathophysiology
mediates the regression
mediates the association
mediates the degradation
mediates the movie
mediates the initiation
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