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The blood vasculature regulates the blood flow and tissue perfusion, and mediates the delivery of nutrients and oxygen to the living tissue [ 1].
When macrophages take up large particles such as zymosan, the calcium sensor synaptotagmin VII (Syt VII) mediates the delivery of supplemental lysosomal membrane to the nascent phagosome, facilitating particle uptake (Czibener et al., 2006).
Thirdly, the same molecule interferes with the accumulation of syntaxin 6, which mediates the delivery of lysosomal hydrolases and the vacuolar proton ATPase to the phagosome (Vergne et al, 2004a).
The study suggested that ZO-1 mediates the delivery of Cx43 from a lipid raft domain to gap junctional plaques, which is an important regulatory step in gap junction formation.
In leaves, none of these transport systems increased in response to salinity and some were not detectable such as the stelar K+-outward rectifying channel (SKORC) that mediates the delivery of K+ from stelar cells to the xylem in the roots towards the shoot.
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Two possible mechanisms (penetration vs nonpenetration) have been proposed in the current literature about how nanostructured substrates mediate the delivery of the predeposited payloads.
These studies demonstrate the importance of mass transfer processes in mediating the delivery of active species in reaction steps for reactions occurring under two-phase conditions.
On the basis of these results, we proposed that SufC ATPase activity works in concert with SufD to mediate the delivery of iron into the Suf pathway.
This amphioxus sequence is therefore a good candidate to mediate the delivery of cholesterol to the inner mitochondrial membrane of amphioxus.
In previous studies, it was shown that BLM disaccharide and BLM monosaccharide, both of which contain the carbamoylmannose moiety, could recapitulate the effects of BLM itself in mediating the delivery of an attached dye selectively to cancer cells.
Although there are numerous hypotheses about the physiological function or functions of ApoE and ApoJ, there is general agreement that they are involved in the clearance of Aβ, likely by mediating the delivery of extracellular Aβ to intracellular compartments responsible for Aβ degradation (that is, lysosomes) [ 27].
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Justyna Jupowicz-Kozak
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