Sentence examples for mediates the cellular from inspiring English sources

HIF-1α mediates the cellular response to hypoxia and thus is a marker of tissue hypoxia.

Intracellular calcium ([Ca2+]i) signaling is an essential universal secondary messenger that mediates the cellular metabolic activity in chondrocytes6,7,8,9,10.

The MRP1 mediates the cellular efflux of various xenobiotics including heavy metals and mediates cellular resistance to heavy metals.

The major transcription factor, which mediates the cellular response to hypoxia, is hypoxia-inducible factor (HIF).

Fleischer, CC, and Payne, CK. "Nanoparticle surface charge mediates the cellular receptors used by protein-nanoparticle complexes". Journal of Physical Chemistry B 116 (2012): 8901-8907.

The loss of MGMT protein was, however, not due to its degradation because the ubiquitin-promoted in vitro degradation of MGMT, which mediates the cellular disposal of the repair protein, was not altered by p53.

Smoothened and Patched mediate the cellular response to the Hedgehog (Hh) secreted protein signal, and oncogenic mutations affecting these proteins cause excess activity of the Hh response pathway.

Gene-specific transcription factors are DNA binding proteins that function at the center of the transcriptional machinery to mediate the cellular phenotype in response to extracellular signals.

These proteins could mediate the cellular uptake of siRNA in vitro, though compared with PTD-DRBD gene silencing was attenuated by endosomal entrapment.

Peptide transporters are integral plasma membrane proteins that mediate the cellular uptake of dipeptides and tripeptides in addition to a variety of peptidomimetics.

Background: 14-3-3 proteins abundantdand and conserved polypeptides that mediate the cellular effects of basophilic protein kinases through their ability to bind specific peptide motifs phosphorylated on serine or threonine.