Sentence examples for mediates the cell from inspiring English sources

Akt (protein kinase B) mediates the cell survival action of growth factors and cytokines in a variety of cell types and blocks apoptosis induced by multiple apoptotic stimuli.

The cells respond by suppression of cell separation and by increased phosphorylation of the MAP kinase Mkc1 (14), which mediates the cell wall integrity pathway.

These findings confirmed the previous studies [ 22, 23, 25- 29] suggesting that GnRH-II may mediates the cell motility and anti-proliferation in gynecologic cancer cell lines.

The transcription factor Hypoxia Inducible Factor 1 (HIF-1) primarily mediates the cell responses to a low oxygen tension playing a crucial role in cancer development [ 11, 12].

Hypoxia Inducible Factor 1 (HIF-1) is the main transcription factor that mediates the cell response to hypoxia through different mechanisms that include the regulation of genes strongly associated with cancer aggressiveness.

Although not tested directly, evidence is mounting that p53, in addition to its other well established functions, mediates the cell cycle arrest and apoptosis that follows the activation of the mitotic checkpoint.

Interestingly, p75NTR mediates the cell-death-promoting tumor necrosis factor (TNF) receptor superfamily, which includes factors such as FasL, TNF receptor (TNFR -I, TNFR -I, CD40, OX40, and TNF.

G-proteins play a central role in cellular communication mediating the cell response to numerous hormones and neurotransmitters.

Cyclin A (CCNA2) was identified as a direct target gene of REV-ERB suggesting that suppression of expression of this cyclin by SR9011 may mediate the cell cycle arrest.

A prominent signaling pathway involved in mediating the cell survival/cell death fate is the nuclear factor-κB (NF-κB) pathway [3].

The results indicate that the mir-shRNAEGFP-SV40-1 is able to mediate the cell subtype-specific knockdown of a chromosomally integrated gene in a genetically heritable manner.