Sentence examples for mediates sensitivity to from inspiring English sources

Another, which is repressed in the aggressive flies, mediates sensitivity to the pheromone with which male flies mark their territory.

However, previous studies have demonstrated that APC mediates sensitivity to cisplatin in multiple tumor types including breast cancer [ 22].

Recent studies suggest that it is not the abundance of receptor, but rather the activation of the EGFR signaling axis that mediates sensitivity to EGFR inhibition, at least in vitro [ 78– 80].

AR overexpression not only mediates sensitivity to low ligand concentrations, but has been demonstrated to convert anti-androgens such as bicalutamide and flutamide from antagonists to agonists via changes in composition of coactivators recruited to the AR promoter.

Among genes with known antioxidant function, the PF3D7_1438900 (thioredoxin peroxidase1), PF3D7_1457200 (thioredoxin 1), and PF3D7_1121600 (EXP1, an exported glutathione transferase which mediates sensitivity to artesunate [ 45]) genes are down-regulated in response to DHA in P. falciparum trophozoites (Additional file 4) and the orthologues in P. berghei (Additional file 5).

The short-wavelength-sensitive (SWS1) pigments mediate sensitivity to light in the violet to UV range.

To determine the mechanism for the ability of Metnase to mediate sensitivity to Topo IIa inhibitors, we investigated whether Metnase levels affected the cellular apoptotic response to adriamycin.

These 680 mutations may also play a role in mediating sensitivity to T20, which binds to a fusion intermediate in gp41.

Interestingly, glucosylceramides appear to mediate sensitivity to heat stable antifungal factor (HSAF), as, in addition to ΔBAR1 mutants, a glucosylceramide synthase deficient mutant of Yarrowia lipolytica is also resistant to HSAF.

Trigeminal expression of TRPM8 mediates sensory input from cold stimuli in and around the oral cavity and was shown to mediate sensitivity to volatile odorants.

Li et al (1997) reported that overexpression of p21WAF1/CIP1 in cells lacking functional retinoblastoma protein might mediate sensitivity to anticancer drugs by inhibiting E2F2 phosphorylation, which contributed to increased S-G2 cell cycle delay and increased cell susceptibility to apoptosis.