Sentence examples for mediates most of from inspiring English sources

Interleukin-8 (IL-8) mediates most of the angiogenic activity induced by human oral squamous cell carcinoma (OSCC) cells.

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that mediates most of the toxic effects of environmental contaminants.

BZA/TNF-α-mediated IL-6 induction in MCF-7 cells was counteracted by silencing aryl hydrocarbon receptor (AhR), known to mediates most of PAH effects.

The H1 receptor (H1R) mediates most of the proinflammatory effects of histamine.

As discussed before, HIF mediates most of the metabolic adaptations to hypoxia.

Malaria triggers a high inflammatory response in the host that mediates most of the associated pathologies and contributes to death.

AMPA receptors mediate most of the fast postsynaptic response at glutamatergic synapses.

Two-component regulatory systems mediate most of the bacterial cells responses to a variety of signals.

γ-Aminobutyric acidA (GABAA) receptors mediate most of the fast inhibitory neurotransmission in the CNS.

Hence, EP1 might mediate most of the toxicity associated with cyclooxygenase-2 and contribute substantially to the cell death pathways in AD and stroke.

The additional diversity incrementally improved the affinities of antibodies raised against human vascular endoethelial growth factor and the structure of an antibody antigen complex showed that tyrosine side-chains are sufficient to mediate most of the interactions with antigen, but a glycine residue in CDR-H3 was critical for providing a conformation suitable for high-affinity binding.