Sentence examples for mediates light from inspiring English sources
Furthermore, the light responsive D- and E-box enhancer elements of the per2 gene are conserved in chicken and mammals, including humans, and a human promoter fragment containing these elements mediates light induction of a reporter gene when transfected into zebrafish cells.
In Arabidopsis, the MRE motif mediates light responsiveness [ 39].
In the fly phototransduction cascade, a DGK member (RdgA) mediates light response inactivation (Hardie, 2007).
A specific genetic contribution to phase delay may arise from polymorphisms in CACNA1C, a calcium channel component which mediates light-induced shifts of circadian phase, perhaps through effects on both GSK3B and also on CREB (CREB mediates light stimulation of the SCN).
The precise mechanism by which it crosses the synapse is still unclear but the N-terminal of the heavy chain mediates light chain entry into the pre-synaptic inhibitory neurone and where it cleaves synaptobrevin (vesicle associated monophosphate 2).
CRY2 is a photolyase-like blue-light receptor that mediates light responses in plants via interaction with the CIB1 (cryptochrome-interacting basic-helix-loop-helix) protein to promote CRY2-dependent floral initiation [ 44].
If synaptically driven excitatory input from ON-bipolar cells mediates light-induced Fos expression, then this circuit should be amenable to pharmacological blockade by L-AP4, an agonist of the mGluR6 receptor which blocks transmission of visual signals between photoreceptors and ON-bipolar cells [30].
In addition, Halo mediates light-driven hyperpolarizations of amplitude>350% of those mediated by RO4 or other G-protein mediated methods such as baclofen administration, which may aid in the observed high performance of Halo in neuronal spike blockade, a highly nonlinear process.
By using RNAi-mediated silencing of each isoform in vivo, we demonstrated that the short isoform (OPN4S) mediates light-induced pupillary constriction, the long isoform (OPN4L) regulates negative masking, and both isoforms contribute to phase-shifting circadian rhythms of locomotor behavior and light-mediated sleep induction.
Chlorophyll, the fundamental molecule mediating light absorption during photosynthesis in plants and bacteria, is also a porphyrin.
It seems related to the ephaptic cross-talk between Aβ fibres mediating light touch and small-myelinated Aδ fibres close to the trigeminal nerve root entry zone, where there a focal demyelination is caused by neurovascular compression.
