Sentence examples for mediates its function from inspiring English sources

79, 80 Interestingly, CD36 has four palmitoylation sites on both N- and C-termini, and it was shown that palmitoylation plays a crucial role in targeting CD36 to lipid rafts, where it mediates its function.

IL18 is another proinflammatory cytokine that shares many biological, structural and functional properties with IL1 [ 20] and mediates its function through its receptor IL18R (IL18R1 and IL18RAP).

It has been proposed that HLA-DM mediates its function by shifting the equilibrium of peptide averse to a peptide receptive state; however, the peptide loading process is still relatively undefined [14], [15].

Metastin has been identified as a metastasis suppressor gene product that mediates its function through a G protein coupled receptor, GPR54.

IL-4 mediates its function by binding to receptors expressed on target cells such as T lymphocytes, and macrophages.

Accordingly, Hfq could be a candidate through which ClpX mediates its function in translational stimulation.

Although ATX is a member of the nucleotide pyrophosphatase/phosphodiesterase family and had been proposed to mediate its activity as a nucleotide phosphodiesterase, it is now established that ATX mediates its functions primarily through production and action of LPA.

Ang II mediates its functions through the stimulation of two distinct receptors, AT(1) (two subtypes in rodents (AT(1a) and AT 1b))) and AT(2).

Insulin mediates its functions via IRS (insulin receptor substrate)–PI3K-dependent pathway [ 24].

NT mediates its functions through its two G protein coupled receptors: neurotensin receptor 1 (NTR1) and neurotensin receptor 2 (NTR2) (high and low affinity receptors, resp).

Estrogen mediates its functions through two specific intracellular receptors, the ERα and the ERβ, which act as hormone-dependent transcriptional regulators [ 10, 11].