Sentence examples for mediates its binding from inspiring English sources

Based on the studies showing that the 40s loop of CCL5 mediates its binding to glycosaminoglycans (GAG), we analyzed the roles of GAG in regulating CCL5 secretion.

Our study is the first to report the erythrocyte binding activity of PfRH2a/b and delineate a region of the native protein that mediates its binding with erythrocytes.

LBP binds to Gram-negative bacteria via the lipid A part of the lipopolysaccharide (LPS) which mediates its binding to the CD14 cellular receptor molecule presented by monocytes and macrophages [12], [13].

Our data also demonstrate that the N-terminal region of HIV-1 Vif mediates its binding not only to the target molecules A3G and A3F but also to A3C and A3DE.

We have found that, despite the evolutionary diversification of the MAGE family, the characteristic hydrophobic surface shared by all MAGE proteins from yeast to humans mediates its binding to NSE4/EID proteins.

In conclusion, we have found that, despite the evolutionary diversification of the MAGE family, the characteristic hydrophobic surface shared by all MAGE proteins from yeast to humans mediates its binding to NSE4/EID proteins.

PGRN is a cysteine-rich protein and proper folding of the protein is critical to mediate its binding to TNFR.

These protein fragments are considered antibody-mimetic because, like antibodies, each protein fragment is composed of a constant region, which stabilizes the overall protein folding, and multiple variable regions that mediate its binding to a specific target.

It is a highly conserved subunit which is loosely associated to the eIF3 complex and might play a role in mediating its binding to the 40S ribosomal subunit (reviewed in [ 2, 4, 5]).

PR mediates its actions by binding ligands, translocating into the nucleus, and directly binding to DNA or nuclear signaling.

This active form binds in the circulation to vitamin D-binding protein (VDBP), to be transported to target organs where it mediates its biological effects by binding to the vitamin D receptor (VDR).