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It mediates its action through interaction with estrogen receptor (ER).
Bromocriptine is unique in that it does not have a specific receptor that mediates its action on glucose and lipid metabolism.
Insulin mediates its action on target organs through phosphorylation of a transmembrane-spanning tyrosine kinase receptor, the insulin receptor (IR).
The present study was designed to demonstrate that delphinidin, an anthocyanin that possess the same pharmacological profile than wine polyphenols in vascular protection, mediates its action via direct activation of ER-alpha receptor.
PGE2 mediates its action by interacting with four subtypes of PGE2 receptors, the EP1, EP2, EP3 and EP4 receptors [50].
One possibility is that HCRT mediates its action via HCRT target neurons in the pons since REM sleep is generated from there [9], [10].
Similar(43)
It mediates its actions via the CCK1 and CCK2 receptors.
IGF2 mediates its actions mainly through the IGF2R, but it also binds to the IGF1R with a lower affinity.
PR mediates its actions by binding ligands, translocating into the nucleus, and directly binding to DNA or nuclear signaling.
NRG-1 mediates its actions through activation of the extracellular domain of the tyrosine kinase receptors, ErbB.
We propose that K1 5 mediates its actions in CIA by preventing the formation of new vessels in the proliferating synovium of the inflamed joints.
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