Sentence examples for mediates integration of from inspiring English sources

In mammalian cells, the enzyme also mediates integration of plasmids bearing attB into native sequences that have partial sequence identity with attP, termed pseudo attP sites.

Integrase mediates integration of a DNA copy of the viral genome into the host chromosome.

This plasmid (50 µg) was co-transfected into 3D7 parasites along with plasmid pHTH (10 µg) for transient expression of the piggyback transposase that mediates integration of the pTEOE plasmid into the parasite genome (Balu et al., 2005).

In the Tol2 transposon mediated gene transfer system (hereafter, the Tol2 system), the Tol2 transposase (T2TP) mediates integration of a transgene cassette flanked by Tol2 cis-sequences into the host genome.

Furthermore, miR-132-3p regulates neuronal outgrowth in response to neurotrophins (Vo et al, 2005), mediates integration of newborn neurons in the adult hippocampus and dentate gyrus (Luikart et al, 2011; Magill et al, 2010), and shapes synaptic structure (Edbauer et al, 2010) and plasticity in the visual cortex (Mellios et al, 2011; Tognini et al, 2011).

The translocons also mediate integration of the transmembrane helix of the integral membrane protein into the lipid bilayer (Park and Rapoport, 2012).

Gomez-Rodriguez, J. et al. Itk-mediated integration of T cell receptor and cytokine signaling regulates the balance between Th17 and regulatory T cells.

Novel techniques that mediate integration of foreign genes at specific pre-determined locations circumvent many problems associated with the existing methods of gene transfer.

We also provide evidence that the enzyme can mediate integration of an incoming plasmid bearing an attB or attP site into endogenous sequences in the human genome.

In this study, we report the generation of tropism-modified dHVs containing AAV rep68 expression units and show their ability to mediate integration of DNA fragments of at least 10.3 kb into the AAVS1 locus on human chromosome 19 in HeLa and muscle progenitor cells.

A study by Bos et al. [ 6] showed that Omp85 of N. meningitidis requires only a single POTRA domain to be functional and mediate integration of OMM proteins [ 6].