Sentence examples for mediates fusion of from inspiring English sources

In the present study, we found that ULK1 mediates fusion of the autophagosome to the lysosome by interacting with STX17.

GP1 mediates host cell attachment and receptor recognition, whereas GP2 mediates fusion of the viral and host membranes8,9,10,11,12.

HIV-1 Env mediates fusion of viral and target cell membranes, but it can also mediate fusion of infected (producer) and target cells, thus triggering the formation of multinucleated cells, so-called syncytia.

The fusion (F) protein mediates fusion of viral and cell membranes and is highly conserved.

Once internalized, HA mediates fusion of viral and host membranes via a low pH- induced structural conformation change [11], [12], [13].

Following binding and endocytosis, the E1 underlying E2 mediates fusion of viral and cellular membranes within the acidic conditions of endosomal compartments [12].

Recent structural advances reveal how very different protein architectures can be used to form trimeric extensions that extend into the target cell membrane and then fold back to mediate fusion of the target and viral membranes.

Recent evidence suggests that members of the SNARE family mediate fusion of cytotoxic granules with the surface of CTLs.

The HA is also responsible for cell entry by mediating fusion of the endosomal and viral membranes.

This process will expose the hydrophobic fusion peptide and mediate fusion of the viral envelope with the host cell membranes [56].

Hence, for the fragmentation of the ER described above to qualify as a physiologically relevant phenomenon, it should be balanced by a mechanism mediating fusion of ER vesicles.