Sentence examples for mediates elimination of from inspiring English sources

Our results show the genetic mechanism through which cell selection mediates elimination of suboptimal but viable cells.

Additionally, the growth medium for ZR-75-1 wasupplementeded with 1 nM β-estradiol (Sigma-Aldrich), and did not contain sodium pyruvate, which mediates elimination of H2O2 from the culture medium [ 21].

Certain immune cells such as neutrophils mediate elimination of foreign organisms such as bacteria and fungi with superoxide that is produced by NADPH oxidases located on the cell membrane [29].

We reasoned that the pi-RISC, by virtue of the enormous sequence portfolio of piRNAs, might mediate elimination of a large variety of mRNAs in late stages of spermiogenesis.

Therefore, the downregulated miR-29 may regulate the T helper 1 (Th1) cell differentiation to secrete more IFN-gamma and mediate elimination of intracellular pathogens, but dysregulated T cell responses may also contribute to pathologic inflammation.

The binding of activated platelets to tumor cells has been shown to hinder natural killer cell mediated elimination of circulating tumor cells [ 21], and the destruction of circulating platelets with antiplatelet antibodies significantly reduces metastatic potential in several murine tumor models [ 22].

41,54,55 Salivary and fecal IgA are considered to represent the common mucosal immune response (secretory IgA) that can prevent initial pathogen entry, while circulating IgA and IgG form a second line of defense, mediating elimination of pathogens that have breached the mucosal surface.

The interaction of the adhesion molecule of the immunoglobulin family intercellular adhesion molecule 1 (ICAM-1) with its ligands such that the integrins LFA-1 and Mac-1 is crucial for the regulation of several physiological and pathophysiological processes like cell mediated-elimination of tumor or virus infected cells, cancer metastasis or inflammatory autoimmune processes.

Phagocytosis, the engulfment of particles, mediates the elimination of invading pathogens as well as the clearance of apoptotic cells.

While autophagy was originally viewed as an inducible cellular mechanism to provide an energy source during short-term starvation, it has subsequently been shown that constitutive autophagy mediates the elimination of protein aggregates or damaged organelles and thus plays a protective role in multiple cell types [2], [3].

Parkin mediates the elimination of the defective mitochondria by autophagosomes [ 129].