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However, when the fusion protein of EspZ with β‐lactamase (EspZ-TEM) translocates into HeLa cells via the T3SS of WT EPEC, it mediates cleavage of CCF2‐AM, which induces a shift from green to blue fluorescence (460 nm).
Further studies suggested that the RF1 protein mediates cleavage of the dicistronic mRNA by binding to the intergenic region, and the processed orf79 transcripts are degraded and unable to associate with ribosome.
A recent work reports that H1 RNA mediates cleavage of precursor tRNA in the absence of protein [15].
CTSD subsequently mediates cleavage of Bid leading to activation of caspase-9 and -3.
Casp3 mediates cleavage of multiple proteins and causes DNA fragmentation which eventually leads to apoptosis [ 2].
Consequently, miR159 mediates cleavage of Myb33 and Myb101 transcripts, which encode positive regulators of abscisic acid (ABA) responses.
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Finally, we systematically compared Josephin-mediated cleavage of K48-linked polyUb chains of increasing length.
Nani, R. R., Gorka, A. P., Nagaya, T., Kobayashi, H. & Schnermann, M. J. Near-IR Light-mediated cleavage of antibody-drug conjugates using cyanine photocages.
Designed to simulate miRNAs, small interfering RNAs represent a powerful genetic approach to potently inhibit gene expression by mediating cleavage of the intended mRNA target.
We designed a truncated RNase P-associated EGS molecule to specifically recognize the U5 region of HIV-1 mRNA and mediate cleavage of hybridized mRNA by the RNase P enzyme.
The primary role of the miRNA is certainly to directly regulate PEG11 mRNA by RISC-mediated cleavage of the PEG11 sense transcript [31].
More suggestions(15)
mediates repression of
mediates internalization of
mediates silencing of
mediates fusion of
mediates biotinylation of
mediates recruitment of
mediates adhesion of
mediates regulation of
mediates stimulation of
mediates export of
mediates recognition of
mediates endocytosis of
mediates upregulation of
mediates proliferation of
mediates effect of
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