Sentence examples for mediates cell proliferation from inspiring English sources

Further analysis is required to clarify whether WNT10A-Frizzled binding mediates cell proliferation in both endothelial cells and stromal cells.

Next, the growth responses to 10nM E2 and 1µM 25HC were abolished by 10µM ICI (Fig. 4F and 4H), suggesting that ERα mediates cell proliferation induced upon exposure to both compounds.

ERβ-selective estrogens might be more desirable for HT than ERα-selective estrogens, because studies indicate that ERα mediates cell proliferation that contributes to breast and endometrial cancer whereas ERβ generally is thought to counteract ERα-dependent ERα-dependentation and tumor formation [21], [22], [23].

Moreover, COX-2 mediates cell proliferation through production of free radicals.

Despite the significant role of ERα, the mechanism of how ERα mediates cell proliferation is not fully understood.

The mechanism of how ERα mediates cell proliferation may have clinical implication for breast cancer etiology and therapy.

These are important molecules in mediating cell proliferation and play a role in the induction of anti-apoptosis mediators.

Moreover, miR-34a-5p regulathe the protective effect of sev-preconditioning in injured H9c2 cells by mediating cell proliferation and cell apoptosis.

Read, R. D. et al. A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.

These enzymes can be targeted to increase expression of tumor suppressors and impede activation of oncogenic signaling pathways mediating cell proliferation and tissue invasion.

Human epidermal growth factor receptor 2 (HER2) is a transmembrane glycoprotein that belongs to the family of epidermal growth factor receptor, mediating cell proliferation and differentiation in the developing embryo and in adult tissues (Cho HS et al., 2003).