Sentence examples for mediates binding of from inspiring English sources

Further, it has been demonstrated that the HSP101 binds to this poly CAA) region and mediates binding of initiation factors eIF3 and eIF4G, thereby promoting translation initiation.

A single conserved residue mediates binding of the ribonucleotide reductase catalytic subunit rrm1 to rrm2 and is essential for mouse development.

Thus, while the colipase fold of Dkk1/2 mediates binding of Dkks to Lrps, the DKK_N domain modulates the outcome of this interaction (Brott and Sokol, 2002).

The NTR domain also mediates binding of PCPE-1 to cells, an interaction inhibited by heparin, thus suggesting involvement of cell membrane heparan-sulfate proteoglycans (HSPGs).

In particular we focus on the structures of two molecules; the erythrocyte binding antigen, EBA-175 involved in erythrocyte invasion and the VAR2CSA protein that mediates binding of infected erythrocytes to the placenta.

SCARB2 mediates binding of EV71 at the cell surface and internalization of the virus via a clathrin-dependent pathway.

Plasmodium falciparum-mediated pathogenesis has been associated with the parasite's ability to mediate binding of its host cell to the vascular endothelium of several organs, notably the brain leading to complications such as cerebral malaria.

Day, C. J. et al. Glycan:glycan interactions: High affinity biomolecular interactions that can mediate binding of pathogenic bacteria to host cells.

HA is knownto mediate binding of viruses to target cells via terminal sialic acid residues in glycoconjugates.

This motif is homologous to sorting signals within host cargo proteins known to mediate binding of AP2M1, the μ subunit of clathrin adaptor protein complex 2 (AP-2), and intracellular trafficking.

That structure has now been exploited for elucidation of interface pharmacophores that mediate binding of CST to its target, with consequent secretory inhibition.