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The kinetochore is a multi-protein complex that assembles at the centromere and mediates attachment of chromosomes to spindle microtubules to ensure accurate chromosome segregation at mitosis.
Furthermore, HWP1 up-regulation may also increase adhesion since Hwp1p is a glycosylphosphatidylinositol cell wall adhesin (GPI-CWP) and mediates attachment of C. albicans cells to human endothelial and epithelial cells [44].
It also mediates attachment of the adhesin Cpa at the tip of the pilus [46] and attachment of the pilus shaft to the basal pilin Spy0130 [47], in each case through amide bond formation.
PilC1 is an adhesin that mediates attachment of N. meningitidis to host cells.
It is hypothesized that the Ndc80 complex directly mediates attachment of kinetochores to spindle microtubules (Cheeseman et al. 2006; Wei et al. 2007; Deluca et al. 2006).
During virus entry the G protein mediates attachment of the virus to the cell [ 11], while the F protein mediates the fusion of the virus and host cell membrane [ 12].
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Integrin αvβ3 was proposed to mediate attachment of Pam3CSK4 to cell surfaces through binding of vitronectin attached to the lipopeptide.
Furthermore, it is a component of hemidesmosomes, which mediate attachment of epithelial cells [38].
Integrins mediate attachment of stem cells to the matrix in the niche.
GOAT is the transferase mediating attachment of octanoate to the appetite-stimulating hormone proghrelin [30], [37] [39].
Further, PIM was suggested to act as adhesins mediating attachment of M. tuberculosis bacilli to non-phagocytic cells [27].
More suggestions(15)
mediates internalization of
mediates silencing of
mediates fusion of
mediates biotinylation of
mediates recruitment of
mediates regulation of
mediates recognition of
mediates stimulation of
mediates export of
mediates endocytosis of
mediates upregulation of
mediates proliferation of
mediates effect of
mediates acidification of
mediates SUMOylation of
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