Sentence examples for mediates an increase from inspiring English sources

This supports our hypothesis that Erk mediates an increase in myostatin expression via increased MEF-2 activity.

For example, a recent study in yeast demonstrated that the repressor Gal80, which mediates an increase in nucleosome density, can repress endogenous target genes under conditions where the nucleosome density increase is prevented [49].

It is known that the stimulation of growth factor receptor-induced PI3K activation mediates an increase in 3-poly-phosphoinositides, which in turn activates downstream effectors, such as the serine/threonine kinase Akt/protein kinase B (Akt/PKB) [32] [34].

Caprin-2 also mediates an increase in VP mRNA abundance, possibly by increasing transcript stability.

Caprin-2 binds to the AVP mRNA, and mediates an increase in the length of the poly(A) tail, either by stimulating further synthesis, or by inhibiting deadenylation.

Therefore, the APC mutation activates the Wnt signal pathway and mediates an increase in miR-224, which may serve as a negative regulator of cell motility and metastasis.

In mice, haploinsufficiency for p27 mediates an increased susceptibility to carcinogens.

Our previous study has shown that chronic activation of endothelial TRPV1 channel, which mediates an increased Ca2+ influx and subsequent phosphorylation of PKA and eNOS.

Overexpression of this protein (termed PfACBP1) in P. falciparum cells mediates an increased resistance to the ionophores which suggests its role in calcium-dependent signaling within the apicoplast.

Here we report that lentiviral mediated Cx36 expression in NPC cultures mediated an increase in neuronal and oligodendrocyte differentiation.

Similalry, excess caloric food intake is sensed by the brain, which will mediate an increase in energy expenditure via adrenergic receptors [34].