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Indeed, the specific interaction between lectins and their corresponding carbohydrate partner(s), either occurring as a free ligand or as part of a glycoconjugate, mediates a multitude of biological processes.
Lysophosphatidic acid (LPA), a naturally occurring phospholipid, mediates a multitude of (patho physiological events [5].
Rapid generation of NO and ROS following pathogen or elicitor challenge mediates a multitude of metabolic and transcriptional alterations including Programmed Cell Death (PCD).
Lysophosphatidic acid (LPA), a naturally occurring bioactive phospholipid, mediates a multitude of (patho physiological events including activation of mitogen-activated protein kinases (MAPKs).
P2X7 is an adenosine-5′-triphosphate (ATP) gated cation channel expressed on haematopoietic cells that mediates a multitude of pro-inflammatory effects.
The ubiquitous second messenger cAMP mediates a multitude of physiological processes, including glucagon signalling, learning and memory and transcriptional regulation [ 1].
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These mediate a multitude of intracellular events including karyokinesis and cytokinesis, which are essential for complete cell division [30].
Exosomes harvested from different cells under different situations have been shown to mediate a multitude of biological effects, including antigen presentation [6], [21], induction of apoptosis [46], and promotion of cancer cell growth [47] as a few examples.
The second messengers cAMP and cGMP mediate a multitude of physiological processes.
The precise mechanisms by which NO modulates synaptic plasticity are still not fully understood, but NO can clearly mediate a multitude of diverse effects (see Steinert et al., 2010 for a review).
The macroscopic ion-selective behavior of K+ channels is mediated by a multitude of physiological factors.
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