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A single F1F2 element mediates weak enhancer blocking, whereas a five times multimerized element (5xF1F2) mediates a more than five-fold robust enhancer blocking.

A probable mechanistic explanation for this observed 3' secondary structure would be that this structure, either through a direct or indirect interaction with the ribosome, mediates a more efficient ribosome drop-off after the mRNA translation is completed.

Subsequently, Utx mediates a more profound H3K27me3 removal and transcriptional activation of these homeobox genes in female cells.

Hence, the current view is that clathrin fulfills a primarily scaffolding/organizational role in yeast, while it mediates a more structural role (in shaping the vesicle) in mammalian cells.

Perhaps, best known for initiating the rearrangement of immunoglobulin and T-cell receptor genes in vertebrates during the differentiation of lymphocytes (Fugmann et al. 2000), DNA splicing also mediates a more dramatic example of chromatin diminution in ciliated protozoa.

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Israel could have asked Egypt, whose new Islamist-led government has close ties to Hamas, to mediate a more permanent cease-fire.

Furthermore, 'allergen-experienced' ILC2s responded better to unrelated allergen than naïve ILC2s, mediating a more severe allergic inflammation (Martinez-Gonzalez et al., 2016).

The expansion of β subcluster genes in reptiles and mammals might have given rise to a higher molecular repertoire to mediate a more diverse and/or complex cell-cell interaction network.

While a direct effect of these mediators on CD8α+ DC cannot be excluded at this point, we hypothesize that it is likely that these compounds mediate a more significant impact on the co-cultured monocytes.

Bevacizumab appears to mediate a more potent effect on perfusion in carcinoid liver metastases than PEGI.

Moreover, memory T cells do not cause GvHD and mediate a more potent GvL when p110δ is inactivated.

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