Sentence examples for mediated via integrin from inspiring English sources

Initial leukocyte rolling is mediated by E- and P-selectin whereas firm adhesion to the vascular wall is mediated via integrin binding with intercellular adhesion molecule-1 (ICAM-1) and VCAM-1, with the latter more important in initiation of atherosclerosis [6,53].

Tumor cell adhesion to extracellular matrix (ECM) proteins plays a major role in the invasion and metastasis of tumor cells, and is mediated via integrin subunits.

The PTHrP-induced changes in adhesion appear to be mediated via integrin subunit expression as manipulation of PTHrP expression caused parallel changes in integrin expression.

Some research has verified with isotope-labeled monoclonal antibodies that chondrocyte phenotype remains may be due to the attachment mediated via integrin, including members of both the β1 and β3 subunit families.

Of four laminins tested (LM-111, -211, -411, and -511), LM-511 induced the most extensive outgrowth from adult DRG neurons in vitro [ 55], mediated via integrin α6 β1.

Because type XVIII collagen can bind to integrins (Faye et al., 2009), we considered the possibility that survival cues mediated via integrin signaling might be deficient in the absence of type XVIII collagen.

For example, stimulation of proliferation of epithelial cells and fibroblasts with epidermal growth factor depends on β1-integrins, whereas VEGF-promoted adhesion and migration of endothelial cells are mediated via integrin- β1, αv β3, and αv β5.

EGF-mediated cell motility and invasion was also reduced, effects mediated via α6 β4 integrin (Deng et al, 2012).

Such acute effects in response to mechanical loading may be mediated via integrin-FAK, Ca2+-mediated signaling, Vps34 and/or PLD.

Many biological activities of ECM in TM are mediated via integrin-ECM interactions [ 51].

In human chondrosarcoma cells, CCN1, CCN2, and CCN3 have been found to enhance cell migration by increasing MMP-13 expression; this is mediated via the αv β3 integrin receptor and FAK-dependent signaling mechanisms [ 64– 64].