Exact(11)
It is known that genetic variability in the gene encoding the intracellular protein UNC-93B, important for TLRs mediated type I interferon production, increases susceptibility to HSE in humans, as well as deficiency in TLR3 [17], [17].
Diabetes mellitus is a complex multi-system disorder that may be classified as autoimmune mediated type 1 diabetes, or as insulin resistance associated type 2 diabetes.
In order to confirm that BALB/c mice used in this study had an IgE mediated type I allergic response and anaphylaxis, plasma histamine concentrations were measured.
PTH, a polypeptide secreted by parathyroid glands, enhances bone formation by increasing TGF-β mediated type I collagen production in osteoblasts.
Cartilage degradation was measured by matrix metalloproteinase (MMP) mediated type II collagen degradation (CTX-II), and MMP and aggrecanase mediated aggrecan degradation by detecting the FFGVG and ARGSV neoepitopes.
In our study, increased production of IgE in BALB/c mice sensitized and challenged with BLG, OVA or PNA illustrates that these mice experienced a IgE mediated type I allergic reaction.
Similar(49)
cGAS-mediated type I IFN production is also essential for tumor surveillance.
This enzyme-mediated type of hydrogel possesses significant advantages of excellent biocompatibility and controllable mechanical strength.
Recently, the porcine DDX41 is reported involved in the dsDNA- and dsDNA-virus-mediated type I IFN signaling pathway in porcine kidney cells (Zhu et al., 2014).
The pathology underlying AR is regarded as IgE-mediated type I allergy characterized by mucosal inflammation that occurs in response to allergen exposure.
The proposed mechanism of enzyme emulsion-liquid-membrane modenzyme emulsion-liquid-membranesion (typenzyme emulsion-liquid-membranetion—consumodeln of substrate and the carrisr-mediated (type 2) facilitation of the generation—permeation of product.
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