Sentence examples for mediated transgene expression from inspiring English sources
Expression of the CAR was shown in human colon epithelium as well as colon cancer illustrating the feasibility of adenoviral transduction and adenovirally mediated transgene expression.
After normalizing for the activity obtained with the CMV driven plasmid it could be observed that the AFP positive cell lines HUH7 and HepG2 were most susceptible to AFP mediated transgene expression, whereas in almost all other cell lines the hCMV enhancer element just boosted basal expression levels in general.
This does not allow cancer cell-alike GR-mediated transgene expression.
The aim of this study was to evaluate cellular changes induced by retrovirus-mediated transgene expression in MSCs in vitro.
Here, we seek to optimize piggyBac-mediated transgene expression and generate a more efficient, user-friendly piggyBac system.
We describe a paradigm in which small amounts of virus delivered intraspinally to newborn mice result in robust rAAV-mediated transgene expression in the spinal cord.
However, such viral vector-mediated transgene expression is often at low levels and can be reduced over time due to low copy numbers and/or chromatin remodeling repression.
Similar to previous reports, hGRK1-mediated transgene expression was limited to photoreceptor cells [36] [37].
From retrovirus-mediated transgene expression it is known that methylation of the long terminal repeat region takes place.
This promoter has previously been used for lentivirus-mediated transgene expression restricted to rodent beta cells [15].
The observation that promoter-mediated transgene expression was downregulated during differentiation raised the question if promoter activities could be restricted to specific cell lineages.
