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Everything we have is already mediated to some extent; it's known to us only because it's been processed and passed on.
These findings are consistent with the possibility that many of the effects of CR are mediated to some degree through the control of protein synthesis and degradation.
Our data show for the first time a new role for CDK11p58 during centriole duplication, probably mediated to some extent by the centrosomal direct or indirect recruitment of Plk1 and Plk4 protein kinases at centrosomes during mitosis.
Leptin and adiponectin is known to be inversely regulated in vivo [30], however, this relationship is not observed in vitro [31], suggesting that the inverse relationship observed in vivo is mediated to some extent by indirect mechanisms.
Sustained activation leads to apoptosis induction, mediated to some extent by autocrine TNF-α.
The effects of Hairy are mediated to some extent by its interaction with CtBP.
Similar(45)
Because Gates has earned the trust of both the "uniforms" and the White House, he has been able to mediate to some degree.
Interestingly, incidence of HCMV transmission and severity of the associated morbidities seem to be reduced during recurrent episodes compared to primary infections [6] [8], indicating that the adaptive immune response is capable to mediate some protection to the foetus.
Thus, cFLIP dysregulation was the only relevant TRAIL-sensitizing activity observed for withanolide E. Heat shock proteins, particularly HSP90, have been reported to mediate some cellular responses to withanolides.
The endothelium-dependent vasorelaxation is largely attributable to NO, whereas the endothelium-independent relaxation is likely to be mediated by some ion channels including voltage-gated K+ channels, big Ca2+-activated K+ channels or voltage-gated Ca2+ channels [ 8, 9].
For instance, in fibroblasts exposed to oxidative stress, PI3K/AkT activation by ROS is mediated, at least to some extent, by p66shc [ 25]; AkT can, in turn, activate mTOR.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com