Sentence examples for mediated to a from inspiring English sources

Although E7 targets all pRb family proteins, its effects on EBP1 expression may be mediated to a large extent by abolishing pRb-mediated transcriptional repression, given that p107 and p130 do not appear to bind to the promoter in the presence of this growth factor.

For decades, it had been, in the writer Jon Savage's lovely phrase, "the teenage news", the primary means by which everything from fashion to politics had been mediated to a mass audience.

Conclusions: The present results confirm the hypothesis of infiltration of irritants to the incisor pulp through the dentinal tubules and suggest that the reported inflammatory reaction and hyperalgesia are mediated, to a large extent, by capsaicin sensitive primary afferents.

Our results strongly suggest that these immunomodulatory effects are mediated to a significant degree by the asymptomatically induction of iBALT in the lungs of recipient mice.

Gene environment interactions are centrally involved in our susceptibility to disease and these influences are likely to be mediated to a large degree via epigenetic regulatory phenomena[9].

In conclusion, we propose a scenario in which hyperglycemia at clinical disease manifestation drives an increase in β-cell mass, mediated to a large extent by residual β-cell proliferation.

Moreover, external and intrinsic motives are mediating, to a greater or lesser degree, this relationship.

It "mediates," to use a favorite Frankfurt School word.

Mandela still hoped to mediate to prevent a war.

Moreover, increased IL-15 activity mediates, to a large extent, the immune response induced by P31-43 in CD [2].

In addition, the biodegradation of RSFs was inflammation-mediated to a certain degree and fibroblasts may play a critical role in this process.