Sentence examples for mediated through this from inspiring English sources

Therefore, the inhibition of Ubc13 by small compounds could limit the response to viral infections mediated through this pathway.

To understand whether DC infection is mediated through this mechanism, we evaluated the ability of DC to acquire T cell surface molecules, CD3 and CD28, by flow cytometry.

Our hypothesis is that protein interactions mediated through this region of p53 may influence p53's ability to direct mitochondrial –associated senescence (MAS).

A subset of proteins co-immunoprecipitating with PepD in both M. tuberculosis and M. smegmatis are predicted to localize to the cytoplasmic compartment, raising the possibility that additional interactions may be mediated through this domain.

We preliminarily attempted to measure the complex I activity in cybrids to test if the toxic effect of 2,5-HD was mainly mediated through this pathway, which is impaired by the LHON mutations.

The observation that in vivo the upregulation of CXCL8_L2 and also CXCa_L1 correlate in time with the expression of CXCR1, may support our earlier hypothesis that their chemotactic activity is mediated through this receptor.

Furthermore, we highlighted that the beneficial effects of TZDs on cisplatin-based therapies are mediated through the suppression of this pathway.

Furthermore, although it is assumed that these IL-12 effects are CD8+ T cell-autonomous, the possibility exists that regulation may be indirectly mediated through the actions of this cytokine on other IL-12 responsive immune cells.

The peristaltic motion of the intestinal wall is mediated through the action of this neurotransmitter.

Whether this is mediated through the same GABAergic mechanism is not addressed, but this early evidence for the therapeutic potential of HDAC inhibitors warrants further investigation.

This was mediated through the recruitment of mucosal macrophages.