Sentence examples similar to mediated through gain from inspiring English sources

Surprisingly, ALS occurs whether the mutant forms have dismutase activity or not, indicating that SOD1 toxicity is mediated through gain-of-function properties (Wang et al., 2009).

PNPLA3-I148M seems to be a loseems-functoon mutation, bet its pathogenic effect appears to be mediated through a gain in function resulting in a suppression of lipase activity.

The association between Western patterns and T2DM appeared to be partly mediated through weight gain.

The results suggest the increased risk of diabetes may be at least partly mediated through weight gain.

The inverse association may be also mediated through weight gain or obesity, which is an established risk factor for T2D.

Transfection of L188Q SFTPC into mouse lung epithelial cells reduced cellular proliferation and enhanced cytotoxicity in vitro, suggesting that the deleterious effect of mutant SP-C was mediated through a gain-of-function mechanism.

These effects of physical activity may be mediated through prevention of weight gain.

A relation among shift work/sleep disturbances, insulin resistance, and T2D may well be mediated through adiposity or weight gain influenced either by disturbances of the hormone systems or by changed dietary and exercise patterns (24).

When mediated through the camera's lens, the realistic dolls gain an uncanny life force, implicating the viewer in an almost pedophilic act of seeing.

Additionally, the promoting role of SOX2 in cell proliferation mediated through CCND1 (cyclin D1) has been demonstrated by gain-of-function and loss-of-function experiments using MCF-7 cells [ 48].

Couples gain parental blessing for their relationship, often mediated through the father; spend time together only in the presence of chaperones; and save physical contact (including kissing and hugging) for after the wedding.