Nevertheless, DNP mediated the expression of Rho family GTPase and induced cancer metastasis.
These two views are incompatible because ER β can also mediate the expression of this gene.
These observations further argue against the solitary regulation of individual genes by T-Ag, and rather support a broader role for this oncogene in mediating the expression of multiple targets that cumulatively impact the metastatic phenotype in CRC.
This suggested that IRF-1 level may mediate the expression of RANTES in cell lines of liver origin.
Further, we identify a key role for Rac1 signalling in mediating this increased N-Cadherin expression.
Using a pharmacological approach [ 16], we demonstrated a key role for the NF-κB pathway in mediating this decrease in KL expression seen in airway epithelial cells.
The 3′ UTR is the site bound by miRNAs, suggesting the possibility that miRNAs may directly mediate the expression of PD-L1.
Furthermore, molecular characterization of OsSND2 suggested that it functions as a master regulator to directly mediate the expression of other MYBs and facilitate cellulose biosynthesis.
Therefore, a pathway that mediates the expression of PhaNPR1 but not downstream of PhaNPR1 may be important to defense against CymMV in P. aphrodite.
At present factors that mediate the expression and activation of HDACs including HADAC3 remain speculative.
