Sentence examples for mediated therefore from inspiring English sources
The mechanism(s) by which potentially harmful effects of allogeneic blood transfusions are mediated therefore remains largely unknown.
The described biological effects are, in contrast to many other known interactions, receptor mediated and therefore very specific for certain cell types.
As it is well established that many of the protein-ligand interactions are water mediated and therefore water plays very important role in determining the specificity as well as affinity.
It may be hypothesised that the effects of age, mode of presentation and anastomotic leak on cancer-specific survival are biologically mediated and therefore likely to be generalisable to other tumour types.
Studying the signaling mechanism(s) through which the diverse effects of TGF- β are mediated is therefore crucial to better understand various cellular processes, and may provide the basis for novel disease treatments.
Proinflammatory cytokines such as IFN- γ contribute to host resistance against T. cruzi, whereas anti-inflammatory cytokine IL-10 has been implicated in mediating susceptibility; therefore, we examined the effect of rSSP4 on Th1/Th2 cytokines production by spleen cells.
As shown in Figure 4J, truncation of the βPS cytoplasmic tail abrogates the interaction with Tkv, suggesting that the integrin-Tkv interaction is mediated intracellularly and therefore could be relevant for the integrin-mediated enhancement of Tkv-mediated Mad phosphorylation.
More of the contact a customer has with the firm is likely to be with the back-office and, therefore, mediated by technology.
The bulk of the literature in these areas has, however, overlooked the fact that most plants form mycorrhizal associations, and that nutrient uptake is therefore mediated by mycorrhizal fungi.
Any effect of the soil properties on the litter conditions is therefore mediated by the pad.
Approaches that promote effective pulmonary T cell mediated immunity are therefore important to evaluate T cell response in mucosal sites where they serve as an important line of defense following respiratory challenge with smallpox virus.
