Sentence examples for mediated the development of from inspiring English sources
These data support our hypothesis that both wild-type and dwarf fibroblasts develop age-associated sensitivity to ROT, but ROT mediated the development of this sensitivity is delayed in the dwarf fibroblasts.
On the basis of previous study results that showed IL-3 and granulocyte-macrophage colony-stimulating factor cytokines mediated the development of erythroid lineages from early burst-forming unit-erythrocytes to red cells in 7 9 days, an 8 day study period was used and JAK2V617F-GFP positive and CD71+/Ter119+ erythroid progenitor cells were analyzed by FACS.
IL-12 is able to shift differentiation of CD4+ Th0 cells towards the Th1 phenotype [ 38], while IL-4 and IL-6 generally mediate the development of Th2 mediated diseases and regulate the Th1 responses by inhibition of interferon- γ (IFN- γ) production [ 39, 40].
These results suggest that FGF signalling mediates the development of the intermediate mesoderm, within which PGC precursors develop; therefore, we investigated the effects on PGCs by performing qRT-PCR on whole embryos.
Upon aberrant and chronic activation, myofibroblasts can mediate the development of fibrosis [16 20].
Cnidarians have many genes that mediate the development of tissues and organs, especially those of the mesoderm, the middle layer, in bilaterians.
Therefore, the present study was designed to determine the degree to which DA receptors mediate the development of tolerance to the locomotor stimulant effects of caffeine.
These results demonstrate that in the pathophysiology of SGVHD, there is a redundancy in the TH17 effector molecules that mediate the development of SGVHD.
Further studies, investigating the role of these identified proteins in recurrent AO will contribute to a more thorough understanding of the molecular mechanisms that mediate the development of this disease.
Recent clinical and animal studies identified candidate mechanisms that may mediate the development of cardiovascular alterations in the setting of IUGR consistent with the hypothesis of perinatal programming [11, 12].
Current evidence indicates that the acute locomotor stimulant effects of caffeine involve dopamine (DA) receptor activation; however, few studies have investigated the role of DA receptors in mediating the development of tolerance to caffeine.
