Sentence examples for mediated the decrease from inspiring English sources

This suggested, as we had expected for mTOR inhibition, that a post-transcriptional block at least partially mediated the decrease in RTA protein.

To establish that the high glucose-induced increase in miR-133a mediated the decrease in PTB protein levels, we introduced the miR-133a precursor and the miR-133a inhibitor into dispersed islet cells by lipofection.

In order to examine whether the NF- κB pathway mediated the decrease in P-gp expression, we used a NF- κB response element luciferase gene reporter assay, in which luciferase activity increases as NF- κB binds to its response element.

Furthermore, De Benedetti and colleagues proposed that IL-6 mediated the decrease in IGF-1 production that was associated with growth defect in transgenic mice and they also showed that circulating IL-6 levels were negatively correlated with IGF-1 levels in JCA [ 33].

DOI: http://dx.doi.org/10.7554/eLife.09275.007 We also studied which kinds of GABA receptors (GABAA or GABAB receptors) mediated the decreasing effect of GABA on presynaptic glutamate release in VTA-DA neurons by examining the influence of the GABAA or GABAB receptor antagonist on the effect of GABA on the frequency of sEPSCs in rats.

It is important to point out that from the current data, it is difficult to conclude which AR might mediate the decrease in MAP (adenosine-mediated vasodilatation).

OsABA8ox1 is proved to play a key role in mediating the decrease of ABA content in submerged rice, which is regulated by ethylene (Saika et al., 2007).

In an attempt to better understand the mechanism mediating the decrease in cell proliferation, we examined whether apoptosis contributes to this decrease.

Furthermore, C/EBPβ has been reported to be induced by proinflammatory cytokines interleukin-1 and tumor necrosis factor-α, and to mediate the decrease of articular cartilage matrix by suppressing the promoter activity of cartilage characteristic genes like cartilage-derived retinoic acid-sensitive protein and type II collagen [50] [52].

This suggests that the suppression of PKR activity indeed mediates the decrease of Bcl-2 induced by palmitate.

Hence, the GhmiRnD promoted cotton fiber elongation by mediating the decrease in ACCD expression and diverting more carbon into fiber growth.