Sentence examples for mediated the binding from inspiring English sources

There is a region of amino acids (-KIQTSFHCC-) that overlapped between the two peptides, thus it is likely the structure formed by the 9 amino acids mediated the binding of Sjc23-LED with the Fc fragment of human IgG.

ScFv-L-Aff mediated the binding of the hapten to HER2 on SK-BR3 cells and from tissue from the SK-BR3 xenograft; however, scFv-L-Aff did not mediate uptake of the hapten in the SK-BR3 xenografted tumors, presumably due to rapid internalization of the HER2/scFv-L-Aff complex.

A TF contains one or more DNA-binding domains (DBDs), which bind specific DNA sequences to mediate the binding of RNA polymerase at the onset of transcription initiation.

FKBP39, a Drosophila homolog, can bind the immunosuppressive drug FK506 and mediate the binding of the target element of JH and showed a dynamic upregulation from 3 hpi to 24 hpi [76].

It remains to be established if the same determinants mediate the binding of other kinesin adaptors (including syntaphilin) or, alternatively, they bind to other regions.

They both present poly-Pro regions, which mediate the binding of profilin actin, followed by G-actin-binding (GAB) domains of the WASP-homology 2 (WH2) type.

The receptor-binding domain of tetanus toxin (THc), which mediates the binding of the toxin to the nerve cells, is a candidate subunit vaccine against tetanus.

H mediates the binding to nerve terminals and the membrane translocation of L into the cytosol, where its substrates, the three SNARE proteins, are localized.

The use of coiled coils to mediate the binding of non-native proteins represents a novel strategy in chaperone design and a new function for coiled coils.

Grafting a polymeric coating onto GNP surface has the role of mediating the binding of drug molecules and, equally important, to provide stability of the particles in biological media.

Thus, our study has identified a peptide motif that mediates the binding of a bacterial protein to TLR2 and highlights the promiscuous nature of TLR2 with respect to ligand binding.