Sentence examples similar to mediated switch of from inspiring English sources

To define if adipose mesenchymal stromal cell (ASC) treatment mediated switching of the pro-inflammatory profile of M1-like macrophages as a means to develop a tailored in vitro efficacy/potency test.

Model for RNA-mediated switch of protein turnover to activate target genes.

Next, we investigated whether Snail, an important transcription factor in regulating cell migration and EMT, was involved in the GMF-mediated switch of EMT phenotype.

NO may destroy the ISC of IRP1, but also promote iron efflux from cells [ 175], suggesting that the NO-mediated switch of IRP1 to its IRE-binding form could represent a homoeostatic response to iron starvation.

These results demonstrate that SUMOylation of RIM1α is a key determinant of rapid, synchronous neurotransmitter release, and the SUMO-mediated "switching" of RIM1α between binding proteins provides insight into the mechanisms underpinning synaptic function and dysfunction.

PSG induction of alternative monocyte activation is of particular importance as it implies a PSG-mediated switching of the immune system from a predominantly TH1 response to a predominately TH2 response which is more compatible with a successful pregnancy [ 32].

The PAX family of genes may ultimately, following Waddington's epigenetic landscape metaphor, be part of an epigenomic mediated switch between cancer initiation and cancer maintenance pathways, which stochastically drive cancer progression, immune system avoidance, acquisition of tumor resistance, and establishment of metastatic disease.

Introduction of acidic residues at the protein DNA interface holds potential for the design of metal-mediated switches for the investigation of functional relationships.

We identified autocrine activation of TGF-β3 signaling as a key effector of ICN-mediated switch in expression of differentiation markers and suppression of transformation.

To gain further insights on how water extracts of I'm-Yunity™ (PSP) might trigger G1/S cell cycle arrest in HL-60 cells, we determined the expression of the retinoblastoma gene product Rb, known to play a pivotal role in controlling the G1/S phase transition via a cyclin kinase-mediated, switch on/off mechanism of the binding of transcription factor E2F [ 33, 43, 44].

In the subsection "Ubiquitin-mediated switch in vesicular trafficking of ligand-activated EGFR": The authors state "The translocation of EGFR to the PM after EGF addition coincided with a loss of EGFR fluorescence at the RE.