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Interestingly, extracts isolated from quiescent liver mediated significantly higher conversion rates than those isolated from regenerating liver.
LPS priming alone caused differential expression of 40 genes and mediated significantly different response to a subsequent E. coli challenge of 226 genes.
ssAAV9 carrying the WPRE sequence mediated significantly more gene expression than its sc counterpart, which lacked the woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) sequence.
Therefore, the association between stress susceptibility and production in the quail, if it exists, is not mediated significantly by major genes involved in the determinism of the duration of tonic immobility measured at a young age.
When E1A-MEF and E1A-Cox2-MEF were loaded with the gp33 peptide and incubated with p14 splenocytes, COX-2 expression again mediated significantly increased clonogenic survival of cancer cells.
The creation of a pro-angiogenic environment in the subretinal space, while mediated significantly by RPE alterations, may also be contributed towards by the subretinal microglia themselves.
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In vitro gene transfection and cytotoxicity experiments in different carcinoma cell lines expressing FGFRs showed that MPC/Ad-SS-PEG could mediate significantly higher transfection efficiency than MPC complexed with adamantyl-PEG (MPC/Ad-PEG), which has no disulfide linkage and is non-PEG-detachable.
Different approaches to use the documented effects of Fcγ receptor polymorphisms have been pursued therapeutically, for example, by modulation of IgG binding to Fcγ receptors via site-directed mutagenesis, mediating significantly higher rates of tumor cell lysis via ADCC (68).
Addition of anti-BAT3 (rabbit polyclonal, [8]) inhibited NK cell mediated cytotoxicity significantly when compared to a rabbit control serum ((p = 0.019); Fig. 2A).
In a previous study [24] an OHT concentration of 50 nM was used to induce mCrem mediated recombination, significantly lower than the 1 µM used in the studies above.
In concurrence with the anti-inflammatory response reported in the above studies, H. pylori DNA administration before the induction of dextran sodium sulfate (DSS) mediated colitis significantly ameliorated the severity of colitis.
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