Sentence examples for mediated sequestration of from inspiring English sources

By contrast, in the presence of NFGAIL-GI, interaction of hIAPP with the lipid membrane is completely abolished, consistent with NFGAIL-GI mediated sequestration of hIAPP via hetero-complexation in the aqueous phase mainly accounting for the observed strong effect of NFGAIL-GI on hIAPP fibrillogenesis at the lipid membrane interface.

Under this scenario, MBNL2-dependent suppression of GFP CUG) 91 mRNA-induced toxicity would be mediated by MBNL2-mediated sequestration of CUG repeat RNA, rather than the other way around as traditionally understood.

An alternative approach is to control the cellular microenvironment through biomaterial-mediated sequestration of cell-secreted proteins important to differentiation.

Gαo-mediated sequestration of Gβ13F/Gγ1 depletes the pool of the heterotrimeric Gs complexes.

Furthermore, we show CXCR7-mediated sequestration of CXCL12 by the endothelium of mouse heart valves and of human umbilical veins.

Collectively, these observations suggest that E-cadherin-mediated sequestration of active β-catenin to the cell surface coincides with induction of PI3-K/AKT activity.

Another disruption mechanism may involve an aptamer-mediated sequestration of RasGAP into aggresomes, according to a recently described phenomenon observed with the hepatitis B virus core protein and the human papillomavirus E6 protein [19].

A melanoma-specific explanation for drug resistance is melanosome-mediated sequestration of cytotoxic drugs that increases drug export.

Activation of ATM following the caveolin-1-mediated sequestration of PP2A-C may not be the only mechanism employed by cigarette smoke to activate p53.

This could be achieved by pharmaceutical inhibition of GSK3 β, by inhibition of the proteasomal degradation pathway, or by antibody-mediated sequestration of Dkk-1.

Nonetheless, our findings suggest an LTBP-1-mediated sequestration of LAP into Notch3-ECD aggregates and point to an involvement of the TGF-β pathway in CADASIL pathogenesis.