There is precedent that internalization of particles or ligands can involve a series of receptors that separately mediate attachment and internalization [46], [47], [48].
A wealth of data suggests that amygdala, insula, and anterior temporal pole are responsible for separately mediating the cognitive, physiological, and experiential aspects of emotional responses, respectively [ 41].
To reveal the mechanism of regulation mediated by the cross-bridges, separately from the effect of Ca2+, we investigated the force-sarcomere length (SL) relationship in rabbit skeletal myofibrils (a single myofibril or a thin bundle) at SL > 2.2 μm in the absence of Ca2+ at various levels of activation by exogenous MgADP (4 20 mM) in the presence of 1 mM MgATP.
This analysis estimates the direct effect of acceleration, sedentary time and MVPA on PWV at 30 years, and the indirect effect that was mediated through BMI, WC, SBP and DBP, separately.
We analyzed variance in relative fitness mediated by early survival and by adult fertility separately, as did other demographic studies involving lifetime fitness measurements [ 10 14, 25].
In the final mediation model, we tested whether HRV mediated the effect of age on neural activity at rest (Fig. 8b, blue colour paths), separately for each frequency band.
So far, the genetic control of rhabdomere formation by chp, prom and eys on the one hand and stalk membrane development, mediated by the Crb complex, on the other hand, was studied separately.
Examining the rates separately for second and third saccades shows that this effect is largely mediated by the third saccade data; indeed the interaction between target location and saccade number was marginally significant, F 1, 5) = 5.08, p = .07.07
