Sentence examples for mediated sensitization to from inspiring English sources
In light of this observation, we hypothesized that one mechanism of IFN-γ mediated sensitization to apoptosis was deactivation of anti-apoptotic Stat3, possibly as a consequence of increased transcriptional activation and expression of Stat1.
To delineate the role of Stat1 in IFN mediated sensitization to apoptosis, sub-lines of the U-266-1970 MM cell line with a stable expression of the active mutant Stat1C were utilized.
To delineate the role of Stat1 in IFN mediated sensitization to apoptosis induced by Fas and therapeutically relevant drugs, we established sub-lines of the IL-6 dependent MM cell line U-266-1970 with a stable over-expression of wild type Stat1 as well as its active mutant Stat1C [ 23].
Non-atopic asthma is widely-accepted to be identifiable from the absence of positive skin prick tests for IgE mediated sensitizations to common allergens which include dust mites, pet and particular foods [ 30].
Taken together, these data show that expression and processing of PIDD are required for E1A-mediated sensitization to NO-induced apoptosis.
Since we identified caspase-2 as the apical caspase activated in response to NO treatment of E1A-positive cells, we next tested the requirement for PIDD expression in the E1A-mediated sensitization to NO-induced apoptosis.
To specifically address whether Bak/Bax are required for E1A-mediated sensitization to NO-induced apoptosis, E1A-positive Bak/Bax-negative BMKs were treated with the chemical-NO donor DETA-NONOate, in the absence or presence of zVAD (Fig. 5c).
Furthermore, the LRRK2-mediated sensitization to cell death in the presence of proteasomal inhibition could be reversed by TORC1 inhibitors.
Both everolimus-mediated sensitization to exemestane and its bone effect may contribute to the positive results of the combination.
Functional knockdown of xaf1 through shRNA is sufficient to eliminate the IFN-β-mediated sensitization to TRAIL in glioblastoma cells.
Additionally, FLAG-MCL-1-expressing cells were less susceptible to flavopiridol-mediated sensitization to cytarabine- or daunorubicin-induced apoptosis.
