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In an alternate mediation model, an interaction term of the possible mediating factor and the recovery indicator was also included in the mediation analysis to account for the possibility of moderated mediation, i.e. that the strength of the mediated relationship is contingent on the value of the recovery indicator [78 80].
The LMM can be used to evaluate the total effect of heavy alcohol consumption on CD4 cell count, however, the mediated relationship is not explicitly modeled with a single LMM.
However, when the primary aim of an analysis is to determine the total effect (i.e. direct and indirect) of an exposure on an outcome of interest, it is unclear what the impact of explicit modeling of the mediated relationship is on power, bias, and on coverage probability for the main research aim.
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The only visible profitability-growth relationship is mediated via investment.
Thus, in the structural-equation model, the independent factors and combined mediated relationships can be examined simultaneously, determining the impact of each of the dependent variables in the appropriate order.
This relationship was statistically mediated (accounted for) by CRP levels.
Indeed, in our dataset these relationships were mediated by associations of BD I with prior psychosis and prior psychiatric hospitalization.
G, M, and Y relationships were considered methylation-mediated if: the p-value obtained from the fourth condition above was > 0.05, indicating no statistically significant association between G and Y after adjustment for M; and the CIT P-value was < 0.05.
Neurocognition was related to activities directly and through a mediated relationship with adaptive competence.
Chaperone client relationships are less clear in the Sgt1-mediated coupling of Hsp90 and SCF complexes.
Perhaps the reason why is the mediated relationships under which they get funded.
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