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Indeed, in a previous study it was shown that retroviral-mediated reintroduction of the RAG1 gene into RAG1−/− mice restored T cells numbers back to levels in wild-type mice, while B cell numbers only increased marginally [ 90].
Upon reperfusion, the reintroduction of O2 leads to xanthine oxidase-mediated superoxide generation due to the presence of xanthine and hypoxanthine [ 87].
Reintroduction of NL1 restored the NMDA/AMPA ratios and NMDAR-mediated EPSCs in NL1 KO slices [ 53].
Taken together, the results of this rescue experiment demonstrate that reintroduction of Cyclin D1 could abrogate the inhibitory effects of miR-15b-mediated cell cycle arrest and apoptosis, suggesting that Cyclin D1 is a major target of miR-15b involved in the malignant progression of miR-15b.
More importantly, upon 1,25(OH)2D3 treatment, reintroduction of MICA, MICB, and ULBP2 reverses the miR-302c- and miR-520c-mediated resistance of malignant cells to the cytotoxicity of NK cells.
Inhibition of c-Abl activity and shRNA-mediated knockdown of c-Abl resulted in markedly elevated DSB rejoining at late repair stages, while reintroduction of c-Abl into c-Abl−/− cells led to decreased rejoining.
This reintroduction of Democritus was well timed.
The reintroduction of grammar schools.
who caused the reintroduction of firearms into Japan.
Simplest of all might be the reintroduction of exit controls.
March marks the welcome reintroduction of the Motherlode Book Club.
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