If so, the recycling of money via bond markets could have very different effects on the world economy from the bank-mediated recycling of previous oil booms.
The primary reason for generating Fc fusions is to extend the half-life of pharmacologically relevant protein or peptide by using the FcRn-mediated recycling of the Fc (Strohl and Strohl, 2012; Strohl, 2015).
As the fungus can also use extracellular nutrients to support its growth, autophagy-mediated recycling of basal cell components might become important when there are only limited nutrient sources available in the environment.
Rab11-mediated recycling of ligand has been implicated in Notch activation in the drosophila.
10.7554/eLife.00411.015 Figure 7. MLL release from RC due to RF3-mediated recycling of RF1 (WT and mutants).
As SNX molecule(s) is an important component of the retromer complex, we speculated that DSNX3 either directly or indirectly controls retromer-mediated recycling of Wls.
Taken together, our results demonstrate that DSNX3 interacts with DVps35 in early endosomes, supporting the view that DSNX3 is involved in retromer-mediated recycling of Wls.
However, context-dependent regulatory mechanisms are well known for Notch pathway, so it is possible that the retromer-mediated recycling of the ligand is required for Notch signaling in some cell types but not the others.
In eukaryotes, several of the fused domains have been implicated in trafficking machinery: the DENN domain is a Rab GEF that is required for Rab35-mediated recycling of endosomal proteins and trafficking of surface proteins to the apical membrane (Allaire et al., 2010).
While at NAs Rab5-GTP elicits the endocytosis of active integrins, on the early endosomal compartment R-Ras-GTP can first trigger the RIN2/TIAM1-dependent activation of Rac1 (this study) and then the RLIP76/Arf6-mediated recycling of Rac1-GTP to lamellipodial protrusions.
