Sentence examples for mediated only through from inspiring English sources

These data suggest that in our model sildenafil effects are not mediated only through the PI3K pathway (Figure 4B).

To the rescue is a recent demonstration that IAP-binding proteins may not necessarily require an IBM for their apoptogenic potential and therefore their apoptotic function is not mediated only through an interaction with the IAPs [18].

Until recently, the FasL- associated apoptotic stimulus was thought to be mediated only through the T lymphocytes [ 81].

This data and the specific binding of HGS-ETR1 to TRAIL-R1 support the theory that HGS-ETR1 activity is mediated only through TRAIL-R1.

Transport of these simple sugars is mediated only through facilitated diffusion by the majority of the transporters from the Hxt family, composed of Hxt1 Hxt17, and Gal2.

It is possible that the reported protective effect of sunlight on the mentioned types of cancer and other diseases are not mediated only through vitamin D but also through other and as yet unknown mechanisms.,, A few years ago Becklund et al. demonstrated that vitamin D supplementation is less efficient than UV radiation in suppressing multiple sclerosis in animals.

These results suggest that the toxic effects of TPEN are mediated only partially through the induction of apoptosis, and potentially invoke other death pathways such as necrosis and autophagy.

These responses are mediated not only through direct substrate/product interactions, but also through allosteric effects.

The association most likely is mediated not only through genetic factors, but also through shared socio-economic and environmental factors affecting life-style e.g. smoking, diet, body mass index, physical activity as well as the use of medical services.

Such control is mediated not only through transcriptional factors, which participate in auto- and cross-regulation self-renewal circuitry (for review, see ref. 70), but also by a handful of chromatin regulators catalyzing histone methylation and demethylation.

These effects are mediated not only through the regulation of cellular PA levels, but mainly by the AO reaction products: aminoaldehydes, GABA (γ-aminobutiric acid) and, markedly, H2O2[ 1, 2, 6, 7, 18].