Sentence examples for mediated negative from inspiring English sources

TOR pathway mediated negative regulation of phosphatase Pph21/22 involved phosphorylation of Tap42, which formed a complex with Pph21/22 to downregulate its activity [32], [33].

This result can be explained by a RAD001 mediated negative feedback loop.

Some pathogens could evade immune surveillance through DC-SIGN mediated negative signal pathway.

However, further investigation of the mechanism of miR-510 mediated negative regulation of PRDX1 is necessary to fully understand their role in tumorigenesis and breast cancer progression.

To assess whether the miR-510 mediated negative regulation of PRDX1 was able to interfere with this primary function, we performed cell viability assay after treatment with H2O2.

In the present study, we looked into the insight of mechanism of Sin3B activation and p53-mediated negative gene regulation under bleomycin-induced DNA damaging conditions.

The model that the Ku-Sir4 recruitment pathway is subject to Rif protein-mediated negative regulation is supported by our findings and reports in the literature.

We hypothesized that adult-onset isolated hypogonadotropic hypogonadism (IHH) might result from an altered central set-point for E-mediated negative feedback.

This decrease in IFN-γ levels could occur in part via TNFα-mediated negative regulation of IL-12 production [ 33].

The mTOR pathway can also be activated downstream of RAS via ERK-mediated negative regulation of the TSC1/TSC2 complex [ 11].

Thus, we find that knockdown of NvSoxB(2) causes a reduction in neural gene expression, including that of the Group A bHLH genes NvAth-like and NvAshA, despite the repression of Notch-mediated negative regulation of these genes.