Sentence examples for mediated modification from inspiring English sources

The NBS mediated modification of purified enzyme resulted in total loss of activity.

Its detailed molecular mechanisms presumably merge into the GPR signaling mentioned above, G αi signaling- (which is GPR's intracellular downstream signaling-) mediated modification of TRP functions [ 28, 35].

Ubiquitin-mediated modification plays a critical role in regulating protein stability (Ciechanover and Schwartz, 1994).

Enzyme-mediated modification sites on numerous substrates could be revealed by large-scale proteomic analysis of enriched peptides.

In our previous studies, we showed that C60 derivatives such as polyhydroxylated C60 derivatives regulate Nrf2 activation possibly by ROS-mediated modification of sulfhydryl groups of Keap1 [11].

NO-mediated modification was maintained for Cys19 and Cys20 single mutants, impaired for the double mutant Cys19/20 and completely absent in triple mutants of Cys19/20/139.

The authors concluded that the NO-mediated modification of enzymatic activity of Glo1 is possibly the consequence of structural changes that are induced by this modification.

We generated a NEMO K285R mutant and compared TRAF6-mediated modification of NEMO in the presence or absence of lysine 285.

It is possible that the H2O2-mediated modification of various amino acids and/or combinations of amino acids could all lead to the inactivation of fLuc.

De Hemptinne et al. [12] investigated the role of all four cysteines in NO-mediated modification of Glo1 and found that replacement of Cys61 by exchange with alanine did not prevent from NO-modification after GSNO treatment, while the Cys139 > Ala mutant, was impaired for NO-mediated modification.

This latter result shows that the plant-soil feedbacks strongly act on microbial community assemblages, mainly through variations in mutualistic associations with plants for Fungi, and plant-mediated modification of soil properties for Bacteria.